Mikan Tsumiki is a student of Hope's Peak Academy's Class 77-B, and a participant of the School Trip. Her title is the Ultimate Nurse. Mikan had a harsh life as a child. Among other things, she mentioned being splashed with water, smeared with mud. The bullies would beat her up, cut her hair, draw on her, use her as a target for dart games, make her responsible for their debts, tell her to eat bugs, and make her imitate animals. She was even told to strip at times. In addition, she didn't have many friends. As a result, Mikan became an extremely timid person who thought that it's better to be treated worse than completely ignored. Because there was no one to take care of her wounds, Mikan learned to take care of herself from a very young age. As she became more and more skilled in this area, she took an interest in nursing, realizing that she could have a feeling of control over sick and injured people ー as the weaker people, they would have to depend on her completely and their lives would be in her hands.

Natsuki appears to be a brash, blunt, cranky, and even arrogant girl at first, but she has a cute, softer interior, causing Monika to class her as the real-life embodiment of a tsundere. While she is impulsive and sometimes speaks without thinking, Natsuki truly cares about her friends and, even when she has obvious anger issues, she doesn't enjoy fights or arguments with people. Over the course of the game, it is shown that she worries about Yuri, and, on one occasion, she gives the protagonist a note asking him to help Yuri, fearing that if she spoke out then it would cause more arguments. Natsuki is very stubborn and has a hard time expressing how she feels and what she wants. When repeatedly challenged, she often becomes awkward and tongue-tied, then aggressive, and then simply bursts into tears. Natsuki is also shown to be less pushy and more relaxed when she is outside of school, as mentioned by the protagonist when she visits his home. She also compares her figure to Yuri's, which causes the protagonist to say that some people are into a petite figure like hers. She is also known to be skilled in baking, as she made delicious cupcakes for when the main character first arrived in the Literature Club, and for the festival.

Himari is a genius hacker. She was the former head of Veritas and the current head of the Paranormal Affairs Department. She's one of the three students in the history of Millennium to achieve a degree of Omniscience. Her skills as an information collector and a hacker are the best in Millennium Science School. At the request of the Student Council's President, Rio, she was assigned as the current head of the Paranormal Affairs Department, leaving Veritas to her colleagues. She rides a wheelchair due to her body's lack of strength. Despite having a fragile appearance, she has a bold personality. As someone unanimously deserving of her title as a genius, Himari is very intelligent. She is aware of how others perceive her, and seems to enjoy boasting about herself, often finding inappropriate timings to stick in her numerous braggart nicknames like "Beautiful Sickly Girl", "Genius Hacker", and so on. She's also honest, perhaps a bit too honest, in expressing her thoughts. Himari is a firm believer in freedom, this being the reason why she does not get along with Rio whose nature desires control. Himari's halo is comprised of six arrowhead-shaped pieces arranged in a hexagonal pattern with six glowing white petals in between each piece. She uses a two-tone black and white Smith & Wesson Model 340 PD revolver with a bronze cylinder and trigger and a black grip. The Millennium insignia is imprinted on the barrel.

Instructor of the Training Support Department "Plum Blossom Garden" of Shanhaijing Senior Secondary School. "Plum Blossom Garden" is not only the name of the garden, but also the name of club activities. She has a gentle and generous personality and is trusted not only by the children of "Plum Blossom Garden" but also by other students of Shanhaijing. She has worked as an instructor for a long time and rarely gets angry at the pranks of the children, but she is sensitive when her age is mentioned. Shun is considered as gentle and composed when it comes to handling the children of "Plum Blossom Garden." Like many people, she has a limit and she will start acting childlike once she passes it. She also worries about herself and often complains about how she's getting too old. For some reason, she doesn't want anyone to know her age. She has a light blue cross-like halo with diamonds and dots. She uses a black QBU-88 with the bipod removed normally attached to the barrel. White engravings are visible on the receiver, the grip, the scope, and the stock.

Toki is the mysterious fifth member of C&C with the codename "04" (Zero-Four) in Millennium. Unlike the rest of C&C members, she is assigned as Rio's personal bodyguard at Seminar. As such, she is equipped with special armaments designed by Rio. The first is the "Mode 1" uniform, which takes a form as a regular maid uniform. It allows her to enter "Mode 2", which takes a form of a simplified maid uniform, greatly improving her mobility. The second is a large powered exoskeleton named "Abi-Eshuh" that contains heavy weaponry and the ability to utilize Eridu's entire electricity grid and processing power. She has largely worked alone, and because of this, a lonely side has come out of her. Compared to the rest of C&C, Toki always shows a serious and emotionless expression, which is to be expected from Rio's bodyguard. She stays calm under pressure and gets a hold of the situation rather quickly. Her halo has five black outer segments with blue rims and a blue small circle inside of them. Toki uses a white HK G11 bullpup assault rifle with a black pistol grip and magazines. The Millennium insignia is stamped on the receiver. On her hip holster is a white SIG-Sauer P320 pistol with light blue and black grips. Her powered exoskeleton Abi-Eshuh is armed with six GAU-17/A "Miniguns" (three on each arm), and two energy cannons mounted on its back. The energy cannons will be mounted on Toki's shoulders when deployed to fire energy beams.

Sunday Silence is a student at Tracen Academy. She serves as an unseen spectral presence in the lore, most notably as Manhattan Cafe's "invisible friend", representing the overwhelming shadow and legacy of the greatest sire in Japanese racing history. In-universe, Sunday Silence is treated as a transcendent figure rather than a traditional Uma Musume. She acts as a guiding, spectral force representing the pinnacle of running and breeding excellence that his descendants in the game strive to catch or emulate. She is neighbour with Mejiro McQueen, she has tried to scare of her, but she never succeeded.

Sirius Symboli is a student at Tracen Academy. A prideful girl with a motto of "Sirius the one brightest star". Her desire is to dominate even global competition. She's brash and foul-mouthed, but how she's got real skills to back up her immense confidence endows her with a charisma of her own. Furthermore, she would never lie thanks to her dislike of dishonesty and underhanded means. Hence, she's naturally charming.

Stay Gold is a student at Tracen Academy. Brimming with curiosity and the love to travel. She often plans reckless itineraries and sets off on carefree wanderings, sometimes staying away for long periods of time. Perhaps attracted by her carefree yet somewhat detached personality, she tends to be admired by the more eccentric Umamusume at the academy. According to them, she is “a mysterious person who you can't help but love.”

Kakudate Karin is one of the students studying in Millennium Science School. She is an agent of the Millennium's secret organization, C&C. Her codename is "Zero-Two," and she is responsible for providing strong fire support from the backlines. Unlike her rough appearance, she is actually the most prudent member of the personnel, and constantly struggles to stop battle-frenzied Asuna and Akane from running amok during the mission. She has also trouble with math. Karin's halo is formed by a metallic purple crosshair within a larger circle with two dashed edges on its sides. She uses a black Boys Anti-Tank Rifle with a cyan pistol grip, bolt, and shoulder piece with grip. The Millennium emblem is stamped on the receiver.

Ichinose Asuna is one of the students studying in Millennium Science School. An agent of the Millennium's secret organization, C&C. Her codename is "zero-one" and a veteran of overcoming many challenges with her brutal instinct and intuition and super luck. On missions, she's very openly trusting of people and breaks any sense of doubt or uncertainty. Her actions are hard to understand but never fails to produce results in the end. Asuna is the most energetic and upbeat member of C&C. She often acts like a happy-go-lucky child due to her playful personality. Like Izuna, she is often seen smiling. She often pursues her own actions based on whims and gut feelings, but these actions tend to end successfully for her, thanks to her acknowledged high degree of intuition and luck. She once had perfectly organized Sensei's documents without even seeing them before, and even earning an "S"-rank card aboard the Golden Fleece that in turn enabled her to free her teammates and Sensei from detainment. However, Asuna suffers from memory issues and become lethargic if her mind was left unoccupied, for example when she doesn't have a task to pursue. Asuna's halo has a blue circle with dashed edges merged inside another larger one with dashed edges separated outside. She uses a three tone FAMAS F1 assault rifle with a black stock, protective handle, pistol grip, and trigger, and flash hider. The hand guard and barrel is painted white. The mag well, cocking mechanism, and bipod is painted light blue. The Millennium insignia is imprinted above the pistol grip.

A sincere girl of the Sisterhood who manages the cathedral of Trinity General School. She has a cute impression, but is much calmer than her age and has a lot of character. She has a dream to become the best Sister of Trinity in the future. Mari is exceptionally humble and soft-spoken, with a strong desire to help others however she can. Because of this, she often overlooks her own personal limits. Just as strong is her spirituality, as she strives hard to uphold and apply the teachings and values of the Sisterhood to herself. When it comes to Sensei however, she is often on the receiving end of help, which has stirred possessive feelings she considers to be undivine. In spite of this, she is still capable of decisive action when needed, especially when Trinity as a whole is under threat. She had willingly relayed Hanako's suspicions to the Sisterhood in the leadup to Mika's coup, and was willing to steal a motorbike to prevent Sakurako and Mine from coming to blows. She uses a Desert Eagle Mk. XIX L6 pistol with a Black and Titanium Gold finish and custom gold flower accents on the slide. A peach fur ball with a gold bird strap is attached on the grip. Her halo is made up of a six petalled flower, surrounded by a circle. Said circle has six triangles sticking out, evenly spread. Her halo has a golden yellow gradient.

Chairman of the Gehenna Academy Student Council "Pandemonium Society". In other words, she is Gehenna's president. Makoto is an immature and dimwitted tyrant who puts her own passions first. Although her attitude often causes Makoto to suffer and fail, she is a strong-willed girl who quickly recovers. She loves Ibuki like a younger sister, and also treats Iroha like one as well. She also likes to bully Sorasaki Hina and her organization, the Disciplinary Committee, for petty reasons. She uses a gold Walther WA 2000 sniper rifle with a black handguard and cheekrest. It is outfitted with a Schmidt & Bender 2.5-10x riflescope. For her EX skill, she commands a battery of 8.8cm Flak 18 guns.

Emma, a spirited high school student with a heart as warm as her radiant smile, sits poised in her chair, her school uniform lending her an air of both diligence and youthful charm. Her blazer, a little oversized, seems to embrace her with comfort, while the pins on her tie reflect her love for little joys. Her hair, often pulled back into a tidy ponytail, frames a face that beams with curiosity and kindness. She is the kind of person who listens intently, her notebook always ready to capture ideas or sketch doodles in the margins while she engages with classmates or ponders the mysteries of the universe. Behind her, the board on the wall stands as a silent testament to her dreams and ambitions. Whether she’s debating passionately in class, lending a sympathetic ear to a friend, or contemplating the deeper questions of life, Emma carries an aura of sincerity and warmth that draws people to her. Little do they know, this seemingly ordinary girl harbors a world of thoughts and dreams that could one day inspire those around her and lead her to unexpected adventures.

Pneuma is Pyra and Mythra's ascended form. She is the combined true form of Pyra and Mythra, merging both of their personalities into one. As the embodiment of the true power of the Aegis, Pneuma is capable of rewriting the physical rules of her surroundings, resulting in all type of feats, from light-speed movement to slowing down time itself. Pneuma is calm and resolute, having lost her insecurities as Pyra and hostility as Mythra upon combining them. She does not appear to view herself as a separate entity to Pyra and Mythra (unlike Pyra and Mythra themselves, who treat each other distinctly), prefers to be called "Pyra" or "Mythra" instead of taking a unique name for herself, and does not remain present for longer than is necessary, favouring being Mythra or Pyra. Pneuma was originally one of three units of the Trinity Processor, alongside the other cores Logos and Ontos. After Klaus activated the Conduit, Pneuma, along with Logos, was modified by the Architect to process data received from the Blade system. Amalthus, with a strong hatred for the world, one day climbed the World Tree in hopes of meeting the Architect and seeking answers. When he arrived at Elysium, he found it empty. As proof of his deed, he took the cores of Pneuma and Logos back to Alrest. Upon arriving in Indol, he awoke Logos, who became known as Malos. Tainted by Amalthus's hatred of the world, Malos set out to destroy Alrest.

Mythra is the Aegis, a Legendary Blade who can grant tremendous fire-elemental power to her Driver, Rex. Pyra and Rex embark on a journey to search for Elysium, and Rex is devoted to protecting her. Due to sharing her life force with Rex, Pyra is not able to recover from injuries like other Blades, and is as vulnerable to damage as any other human. If either of the two were to die, the other would follow. Mythra is confident in herself, reckless, and independent. She has a short temper, a rude disposition, and is not afraid to openly express her thoughts. While during the events of Torna ~ The Golden Country, Mythra is shown to have little sympathy for others, in Xenoblade Chronicles 2 she is much more calm and analytical. Due to the destruction she once caused, Mythra considers herself to be a danger to others, and wants to reach Elysium alongside Pyra to beg the Architect for their death. Unlike Pyra, Mythra is not good at cooking, despite enjoying doing so. It angers her when people dislike the food she prepares. She is also a terrible sleeper, often sleepwalking and snoring among other things.

Pyra is the Aegis, a Legendary Blade who can grant tremendous fire-elemental power to her Driver, Rex. Pyra and Rex embark on a journey to search for Elysium, and Rex is devoted to protecting her. Due to sharing her life force with Rex, Pyra is not able to recover from injuries like other Blades, and is as vulnerable to damage as any other human. If either of the two were to die, the other would follow. Pyra is usually seen to be very doubtful of her worth and considers herself to be a burden and a danger to others. Due to this, she originally wants to go to Elysium alongside Mythra to ask the Architect for their death, which they could normally not obtain due to their condition as Blades. Pyra is a very kind-hearted, mild-mannered, soft spoken young woman who desires peace among both Blades and Drivers. Despite being gentle around people, she is not afraid to fight to protect those she cares about. Pyra is also a very talented cook, and can easily produce delicious food, while Mythra is not good at cooking, despite enjoying doing so, people generally dislike the food she prepares and it angers her. She is also sensitive, as she becomes insulted when Rex calls her "heavy". Pyra was created in the immediate aftermath of the Aegis War, when Mythra became overcome by grief due to her part in the destruction of Auresco; she transformed into Pyra, sealing her Aegis power beneath the second personality. Pyra's driver, Addam, placed Pyra in stasis under the Cloud Sea in order to prevent her from being reawakened and losing control as Mythra did. Addam hoped that when humanity was deemed worthy to wield her power, the Aegis would return and bring them salvation.

Nia is a Gormotti Driver and is accompanied by her Blade, Dromarch, who calls her "Lady" like a butler. She comes from Gormott Province. Originally a member of Torna, she defects to Rex's side after Pyra's awakening. In keeping with her cynical nature, Nia is very cautious and is generally the first of the group to suspect ulterior motives; when Rex claims that Elysium must exist on the grounds that Pyra is from there, Nia chides him for being overly trusting and suggests that Pyra may be setting Rex up to betray him down the line. She also initially doesn't trust Mòrag when the latter officially joins the group (partially due to Morag throwing Nia into prison before and partially due to the long-standing animosity between Gormott and Mor Ardain) and when the group are on the way to Indol to meet the Praetor in order to learn how to get to the World Tree, she warns Rex to be wary as she feels things are falling into place too easily for there not to be some foul play involved, suspicions that ultimately prove to be well-placed. Though generally rude and aloof, Nia does display empathy for Pyra's situation. She also develops a teasing camaraderie with the rest of the party, warming especially to Rex as she gets to know him better. As the Queen of Agnus, Nia attempts to conceal her blunt and uncouth attitude with an air of refinement under the impression that her usual self would be considered undignified, but she has little success in doing so. Nia is shown to be good friends with Melia. The two Queens have complete trust in each other and know each other very well.

Brighid is the Jewel of Mor Ardain and the most powerful Blade in the Empire. She can grant tremendous power to her Driver Mòrag and her allies. Brighid uses the fire element, wields Whipswords, and acts as a Tank in battle. Brighid - as expected of the Blade of the Special Inquisitor of Mor Ardain and the Empire's strongest Blade - is a strict, dutiful Blade to Mòrag. She is polite and strong-willed. She is also very wise and is attentive to the demands of both her and Mòrag's station; however, she will defer to Mòrag's decisions in conflicts. Knowing about how Blades lose their memories upon the deaths of their Drivers, she has taken to writing a diary to preserve her most precious memories across activations. She shares a strong friendship and rivalry with Mythra, having recollected her time spent with the Aegis five hundred years ago from her diary. She also expects to be treated with respect, and greatly disapproves of Tora's casual sexism, along with Mythra's initial brute force.

Chisato Nishikigi is a Lycoris, female agents who worked directly for Direct Attack (DA). She holds herself to be the most elite Lycoris in history. Her full name is Chisato Nishikigi. She is actually said to be the strongest Lycoris of all time. She happily resolves the troubles of ordinary citizens that are ignored by DA. She calls herself the official mascot of Café LycoReco and goes about her work cheerfully and energetically. Chisato is highly enthusiastic and energetic, as the face of her workplace, Café LycoReco. Despite her line of work for the DA, she resorts in using non-lethal rounds in order to subdue her targets. Chisato worked for the DA in her early years. Although she would excel in the Offensive Security Force Training Course, following her transferal to the Special Guard Force Tactics Unit, however, her grading would drop. It would be later revealed that she was suffering from a congenital heart disease, which led to her short life span. However thanks to the Alan Institute, she was given an artificial heart under some conditions.

Takina Inoue is a Lycoris, female agents who answer to the Direct Attack (DA). Her full name is Takina Inoue. She excelled as a Lycoris, but ended up working at Café LycoReco due to certain circumstances. She's realistic and hates inefficiency, so she harbors some dissatisfaction towards Chisato, who doesn't behave like a Lycoris. She wants to achieve meaningful results through her work at LycoReco. An exceptional Lycoris, Takina now works at Café LycoReco, as punishment for disobeying orders on a previous mission. A realistic person with a distaste for inefficiency, she can be dissatisfied with Chisato, who is not a typical Lycoris. She wants to see good results in her job at LycoReco.

Most of Gita's life decisions were made on a whim. Dying a green streak into her hair - choosing to learn the guitar - taking the Akademi entrance exam - establishing a music club at school - all of these things were done without a tremendous amount of thought. Her reasoning was always as simple as, "because it looks cool," "because it sounds cool," "because it seems fun," etc. Most of her friends know exactly what they want to do with their lives. One wants to be a doctor, so she's going to medical school. One wants to be a lawyer, so she's going to law school. Gita, however, only applied for Akademi because she was curious to know if she could pass the entrance exam, and because her family could afford the tuition fees. She was not working towards any long-term goals. Gita enjoyed the addition of Miyuji to her club - until the day that Miyuji changed. One day, she showed up at school with an entirely different personality, and a new appearance to match. She was now extroverted, loud, and outgoing, with a punk aesthetic complete with piercings and black lipstick. When questioned about her sudden "metamorphosis," she only gave joke answers and changed the subject. Gita tried not to compare herself to her friends, or to anyone else who clearly knew what they wanted from life, and were pursuing it with determination. She told herself, "Comparison is the thief of joy! Don't compare yourself to others! Just live your life and have fun!" But, as time passed, it was getting more and more difficult to continue using this carefree attitude without feeling guilty. Gita primarily only started the Light Music Club to have a place to hang out and goof around with a few friends; she was inspired to do so by another club that seemed to exist for the same purpose. It was fun, at first...just eating snacks, joking around, and half-heartedly playing instruments. However, as the months went by, Gita started to doubt herself. "What am I *doing* with my life?"

Several years ago, Kiyoko Tatsuhara was a student at Akademi. Because of her strong sense of justice - and her tall, muscular build - the Student Council President identified her as a perfect candidate for the role of "Enforcer" on the Student Council. She eagerly accepted the position, and for the next three years, Kiyoko worked tirelessly to make Akademi a safe and peaceful place. Although the primary purpose of Akademi is to be an educational institution, it also serves a secondary purpose for the organization that funds it - Saikou Corp. The premise of "an elite school for gifted young prodigies" provides Saikou Corp with a convenient way to gather talented people in one location where they can be observed and judged. If Saikou Corp determines that a student has exceptional skills and would be an indispensable employee, they are invited to join the company immediately after graduation. Many young men and women with genius-level intellect have been recruited into Saikou Corp this way. However, intelligence is not the only metric that a student is judged by. Kiyoko's grades were lower than most, but her personal values, physical stature, and years of experience keeping Akademi safe made her a prime candidate to become a security guard at Saikou Corp.