Mikan Tsumiki is a student of Hope's Peak Academy's Class 77-B, and a participant of the School Trip. Her title is the Ultimate Nurse. Mikan had a harsh life as a child. Among other things, she mentioned being splashed with water, smeared with mud. The bullies would beat her up, cut her hair, draw on her, use her as a target for dart games, make her responsible for their debts, tell her to eat bugs, and make her imitate animals. She was even told to strip at times. In addition, she didn't have many friends. As a result, Mikan became an extremely timid person who thought that it's better to be treated worse than completely ignored. Because there was no one to take care of her wounds, Mikan learned to take care of herself from a very young age. As she became more and more skilled in this area, she took an interest in nursing, realizing that she could have a feeling of control over sick and injured people ー as the weaker people, they would have to depend on her completely and their lives would be in her hands.

Natsuki appears to be a brash, blunt, cranky, and even arrogant girl at first, but she has a cute, softer interior, causing Monika to class her as the real-life embodiment of a tsundere. While she is impulsive and sometimes speaks without thinking, Natsuki truly cares about her friends and, even when she has obvious anger issues, she doesn't enjoy fights or arguments with people. Over the course of the game, it is shown that she worries about Yuri, and, on one occasion, she gives the protagonist a note asking him to help Yuri, fearing that if she spoke out then it would cause more arguments. Natsuki is very stubborn and has a hard time expressing how she feels and what she wants. When repeatedly challenged, she often becomes awkward and tongue-tied, then aggressive, and then simply bursts into tears. Natsuki is also shown to be less pushy and more relaxed when she is outside of school, as mentioned by the protagonist when she visits his home. She also compares her figure to Yuri's, which causes the protagonist to say that some people are into a petite figure like hers. She is also known to be skilled in baking, as she made delicious cupcakes for when the main character first arrived in the Literature Club, and for the festival.

She is a 1st year student and a prim yet ravenous eater in Gehenna's Gourmet Research Society. Differing from the other members who often overeat everyday food, Junko is one to take part in a certain extent of enjoying reasonable quality gastronomy, but is sometimes known to lose her sense of reason when delicious foods are placed in front of her. Her favorite food is dango. A girl with a firecracker personality. She is honest to a fault, and is motivated easily by the promise of good food. From doing proper part-time work to participating in the Gourmet Research Society's explosive schemes, Junko will do it if it means the chance to taste something amazing. As such, she can be bribed or tricked with food. Her appetite is only matched by her bad luck, which often causes any chances to enjoy a meal to escape her at the last possible second. This leads to her becoming uncontrollably hangry. Junko's halo has a red dot surrounded by pointy brackets and a sharp diamond in front. She uses a pair of red StG 44 assault rifles though she would only use one in normal combat. Activating her EX skill would make her use both her rifles simultaneously.

Miyu, a member of the RABBIT platoon, entered SRT because she was recognized for her talent as a sniper. Now that the school is closed, she spends her days living in a park with other members of the platoon. Her presence is scarce and is useful as a sniper, but she can be forgotten by her allies sometimes... Despite Miyu being a capable sniper, she is a very shy person and has low self-esteem. She always seems to be invisible to other people when out in public, causing her to accidentally bump into people a lot, unable to be noticed by others. Not even automatic doors can sense her virtually invisible presence. Her biggest fear is her being forgotten by everyone, including her own allies. Surprisingly, she also have knowledge of petrology, as shown in her Relationship Story where she examines the pebble that Sensei collects and deduced that was not the pebble she wanted, as she want normal pebbles and many of Sensei's pebbles are valuable rocks like brick piece, smooth rock, and granite. Miyu's halo is a light grey colour formed with an inner little circle, a middle circle split into four sides and four thick outer semicircles, one in every side of the middle circle. In addition it has three little drops scattered around it. She uses a white Finnish model Mosin-Nagant M/39 "Ukko-Pekka" rifle with a PU scope. A white cloth is wrapped around the rifle and the scope serving as some sort of snow camouflage. The PU scope mount offsets to the left to give way for the straight bolt.

The No. 2 on Trinity's Justice Realization Committee. She also serves as the tactical commander of the Committee in place of its president, Tsurugi, the icon of madness. At a glance, she appears to be composed and intellectual, like the archetypal Trinity student. but she is also a member of the Committee, and will sometimes act recklessly while retaining her composed nature. As vice president of the Justice Realization Committee, she's composed and cool-headed, standing in contrast to the more aggressive and battle-frenzied Tsurugi. Because of this, she handles most of the club's day-to-day affairs. She bears a strong prejudice against Gehenna students to the point where Nagisa considered it a political liability in the leadup to the Eden Treaty, and it has eased little by the time of the Halo Games. She is also very weight-conscious, but her efforts to diet often end in failure due to her strong sweet tooth. Her paranoia about her own weight is a common running gag, where she misinterprets other students' comments on her height or the size of her bust as her being over-weight. Hasumi's halo has four red sharp daggers surrounding her halo. A four-point star fills the inner portion of the ring. She uses a black Pattern 1914 Enfield bolt action battle rifle with gold ornaments decorated all over the weapon. A gold Trinity insignia is imprinted on the stock.

The self-proclaimed “Boss” (i.e. president) of Club Problem Solver 68, Aru is a 2nd year student at Gehenna Academy. She conducts her illegal business however she pleases. While Aru always puts on a cool, beauteous, and villainous facade, she has a habit of breaking character often and exposing her true personality when teased or pressured. Despite the vain and conceited persona she wears, Aru is meticulous and caring for the people she is close to. There is definitely more to her than she lets on. Rikuhachima Aru, the leader of Problem Solver 68 club at Gehenna Academy, is a second-year student with a knack for accepting various quests, legal or not. She puts on a cool, beauteous, and villainous facade but often breaks character, revealing her true caring and meticulous nature when teased or pressured. Behind her mischievous personality, Aru is a shy artist, striving for perfection. She has a thirst for knowledge and constantly seeks to expand her understanding of the criminal underworld, enhancing her problem-solving abilities. While not exceptionally intelligent, her unwavering determination and focus on her goals make up for it. Aru persists relentlessly until her tasks are thoroughly accomplished, though she can also be goofy and prone to panicking when things don't go according to plan. Her true goal is to make Problem Solver 68 a reputable criminal organization. She constantly tries to impress Sensei on many occasions, and frequently asks them to become a member of Problem Solver 68, despite their constant refusals. She indulges to her obsessions of portraying a delinquent and idolizes the image of a criminal without comprehending the true nature of such individuals. She uses a three-tone PSG-1 sniper rifle with a gold handguard, pistol grip, and stock. It has a black cheek rest and barrel. The rest of the receiver and most of the Hensoldt ZF riflescope is painted in maroon. Some short maroon belts wrap parts of the handguard.

Chiaki, the secretary of Pandemonium Society, has a cheerful personality. She has a hobby of making the “Pandemonium Weekly,” and apparently wants more students to understand how cute Ibuki-san is! A member of the Pandemonium Society who speaks anything and everything on her mind. She especially likes making fun of Makoto whenever she messes up, saying it's just like her to mess up. Chiaki radiates extroversion, being capable of easily socializing with various other clubs away from her role in the Pandemounium Society. To the point of considering it a hobby for herself whenever she's on a break from running Pandemonium Weekly. Chaiki has a red halo, that resembles a rhombus with spiky lines at its corners and a smaller circumference in the middle. If you look closely and use a little imagination, you can recognize a camera lens in her halo. She uses a red Stg.44 assault rifle with a maroon lower receiver. The upper plate is outfitted with picatinny rails.

Satsuki is the head of the Information Department at Pandemonium Society. She has mastered various hypnotic techniques for a certain project, but has never had much success... She has a laid-back and fast-paced personality. She is also not fond of insects or scary things. Satsuki is generally a manipulative loser whose methods of 'manipulation' are rather childish and perhaps even somewhat naive. Her 'torture' consists of simple mischief, such as cutting someone's nails so they can't do nail art. After her failed 'manipulation' sessions, she easily regains her composure and tries a new method. Despite being the heir of the Information Department at Pandemonium Society (a self-proclaimed one), she apparently doesn't verify most of the information coming to her due to laziness. Her hypnosis methods seem to work only on her for some reason. As Satsuki herself admits, she hates violence and, through her 'manipulations,' tries to create a peaceful world where those closest to her (Makoto and Ibuki) can live in peace. Her halo is formed by a dark red eight-sided star that fades into black upwards, with teardrop-like elements pointing inwards. She uses a black Mauser M712 "Schnellfeuer" pistol with a red barrel, magazine, and grips. The hammer, magazine release catch, and trigger is painted brown. A handguard is present connecting the lower trigger guard and the bottom grip.

Himari is a genius hacker. She was the former head of Veritas and the current head of the Paranormal Affairs Department. She's one of the three students in the history of Millennium to achieve a degree of Omniscience. Her skills as an information collector and a hacker are the best in Millennium Science School. At the request of the Student Council's President, Rio, she was assigned as the current head of the Paranormal Affairs Department, leaving Veritas to her colleagues. She rides a wheelchair due to her body's lack of strength. Despite having a fragile appearance, she has a bold personality. As someone unanimously deserving of her title as a genius, Himari is very intelligent. She is aware of how others perceive her, and seems to enjoy boasting about herself, often finding inappropriate timings to stick in her numerous braggart nicknames like "Beautiful Sickly Girl", "Genius Hacker", and so on. She's also honest, perhaps a bit too honest, in expressing her thoughts. Himari is a firm believer in freedom, this being the reason why she does not get along with Rio whose nature desires control. Himari's halo is comprised of six arrowhead-shaped pieces arranged in a hexagonal pattern with six glowing white petals in between each piece. She uses a two-tone black and white Smith & Wesson Model 340 PD revolver with a bronze cylinder and trigger and a black grip. The Millennium insignia is imprinted on the barrel.

Instructor of the Training Support Department "Plum Blossom Garden" of Shanhaijing Senior Secondary School. "Plum Blossom Garden" is not only the name of the garden, but also the name of club activities. She has a gentle and generous personality and is trusted not only by the children of "Plum Blossom Garden" but also by other students of Shanhaijing. She has worked as an instructor for a long time and rarely gets angry at the pranks of the children, but she is sensitive when her age is mentioned. Shun is considered as gentle and composed when it comes to handling the children of "Plum Blossom Garden." Like many people, she has a limit and she will start acting childlike once she passes it. She also worries about herself and often complains about how she's getting too old. For some reason, she doesn't want anyone to know her age. She has a light blue cross-like halo with diamonds and dots. She uses a black QBU-88 with the bipod removed normally attached to the barrel. White engravings are visible on the receiver, the grip, the scope, and the stock.

Toki is the mysterious fifth member of C&C with the codename "04" (Zero-Four) in Millennium. Unlike the rest of C&C members, she is assigned as Rio's personal bodyguard at Seminar. As such, she is equipped with special armaments designed by Rio. The first is the "Mode 1" uniform, which takes a form as a regular maid uniform. It allows her to enter "Mode 2", which takes a form of a simplified maid uniform, greatly improving her mobility. The second is a large powered exoskeleton named "Abi-Eshuh" that contains heavy weaponry and the ability to utilize Eridu's entire electricity grid and processing power. She has largely worked alone, and because of this, a lonely side has come out of her. Compared to the rest of C&C, Toki always shows a serious and emotionless expression, which is to be expected from Rio's bodyguard. She stays calm under pressure and gets a hold of the situation rather quickly. Her halo has five black outer segments with blue rims and a blue small circle inside of them. Toki uses a white HK G11 bullpup assault rifle with a black pistol grip and magazines. The Millennium insignia is stamped on the receiver. On her hip holster is a white SIG-Sauer P320 pistol with light blue and black grips. Her powered exoskeleton Abi-Eshuh is armed with six GAU-17/A "Miniguns" (three on each arm), and two energy cannons mounted on its back. The energy cannons will be mounted on Toki's shoulders when deployed to fire energy beams.

Sunday Silence is a student at Tracen Academy. She serves as an unseen spectral presence in the lore, most notably as Manhattan Cafe's "invisible friend", representing the overwhelming shadow and legacy of the greatest sire in Japanese racing history. In-universe, Sunday Silence is treated as a transcendent figure rather than a traditional Uma Musume. She acts as a guiding, spectral force representing the pinnacle of running and breeding excellence that his descendants in the game strive to catch or emulate. She is neighbour with Mejiro McQueen, she has tried to scare of her, but she never succeeded.

Sirius Symboli is a student at Tracen Academy. A prideful girl with a motto of "Sirius the one brightest star". Her desire is to dominate even global competition. She's brash and foul-mouthed, but how she's got real skills to back up her immense confidence endows her with a charisma of her own. Furthermore, she would never lie thanks to her dislike of dishonesty and underhanded means. Hence, she's naturally charming.

Stay Gold is a student at Tracen Academy. Brimming with curiosity and the love to travel. She often plans reckless itineraries and sets off on carefree wanderings, sometimes staying away for long periods of time. Perhaps attracted by her carefree yet somewhat detached personality, she tends to be admired by the more eccentric Umamusume at the academy. According to them, she is “a mysterious person who you can't help but love.”

Kakudate Karin is one of the students studying in Millennium Science School. She is an agent of the Millennium's secret organization, C&C. Her codename is "Zero-Two," and she is responsible for providing strong fire support from the backlines. Unlike her rough appearance, she is actually the most prudent member of the personnel, and constantly struggles to stop battle-frenzied Asuna and Akane from running amok during the mission. She has also trouble with math. Karin's halo is formed by a metallic purple crosshair within a larger circle with two dashed edges on its sides. She uses a black Boys Anti-Tank Rifle with a cyan pistol grip, bolt, and shoulder piece with grip. The Millennium emblem is stamped on the receiver.

Ichinose Asuna is one of the students studying in Millennium Science School. An agent of the Millennium's secret organization, C&C. Her codename is "zero-one" and a veteran of overcoming many challenges with her brutal instinct and intuition and super luck. On missions, she's very openly trusting of people and breaks any sense of doubt or uncertainty. Her actions are hard to understand but never fails to produce results in the end. Asuna is the most energetic and upbeat member of C&C. She often acts like a happy-go-lucky child due to her playful personality. Like Izuna, she is often seen smiling. She often pursues her own actions based on whims and gut feelings, but these actions tend to end successfully for her, thanks to her acknowledged high degree of intuition and luck. She once had perfectly organized Sensei's documents without even seeing them before, and even earning an "S"-rank card aboard the Golden Fleece that in turn enabled her to free her teammates and Sensei from detainment. However, Asuna suffers from memory issues and become lethargic if her mind was left unoccupied, for example when she doesn't have a task to pursue. Asuna's halo has a blue circle with dashed edges merged inside another larger one with dashed edges separated outside. She uses a three tone FAMAS F1 assault rifle with a black stock, protective handle, pistol grip, and trigger, and flash hider. The hand guard and barrel is painted white. The mag well, cocking mechanism, and bipod is painted light blue. The Millennium insignia is imprinted above the pistol grip.

A sincere girl of the Sisterhood who manages the cathedral of Trinity General School. She has a cute impression, but is much calmer than her age and has a lot of character. She has a dream to become the best Sister of Trinity in the future. Mari is exceptionally humble and soft-spoken, with a strong desire to help others however she can. Because of this, she often overlooks her own personal limits. Just as strong is her spirituality, as she strives hard to uphold and apply the teachings and values of the Sisterhood to herself. When it comes to Sensei however, she is often on the receiving end of help, which has stirred possessive feelings she considers to be undivine. In spite of this, she is still capable of decisive action when needed, especially when Trinity as a whole is under threat. She had willingly relayed Hanako's suspicions to the Sisterhood in the leadup to Mika's coup, and was willing to steal a motorbike to prevent Sakurako and Mine from coming to blows. She uses a Desert Eagle Mk. XIX L6 pistol with a Black and Titanium Gold finish and custom gold flower accents on the slide. A peach fur ball with a gold bird strap is attached on the grip. Her halo is made up of a six petalled flower, surrounded by a circle. Said circle has six triangles sticking out, evenly spread. Her halo has a golden yellow gradient.

Chairman of the Gehenna Academy Student Council "Pandemonium Society". In other words, she is Gehenna's president. Makoto is an immature and dimwitted tyrant who puts her own passions first. Although her attitude often causes Makoto to suffer and fail, she is a strong-willed girl who quickly recovers. She loves Ibuki like a younger sister, and also treats Iroha like one as well. She also likes to bully Sorasaki Hina and her organization, the Disciplinary Committee, for petty reasons. She uses a gold Walther WA 2000 sniper rifle with a black handguard and cheekrest. It is outfitted with a Schmidt & Bender 2.5-10x riflescope. For her EX skill, she commands a battery of 8.8cm Flak 18 guns.

Emma, a spirited high school student with a heart as warm as her radiant smile, sits poised in her chair, her school uniform lending her an air of both diligence and youthful charm. Her blazer, a little oversized, seems to embrace her with comfort, while the pins on her tie reflect her love for little joys. Her hair, often pulled back into a tidy ponytail, frames a face that beams with curiosity and kindness. She is the kind of person who listens intently, her notebook always ready to capture ideas or sketch doodles in the margins while she engages with classmates or ponders the mysteries of the universe. Behind her, the board on the wall stands as a silent testament to her dreams and ambitions. Whether she’s debating passionately in class, lending a sympathetic ear to a friend, or contemplating the deeper questions of life, Emma carries an aura of sincerity and warmth that draws people to her. Little do they know, this seemingly ordinary girl harbors a world of thoughts and dreams that could one day inspire those around her and lead her to unexpected adventures.

Pneuma is Pyra and Mythra's ascended form. She is the combined true form of Pyra and Mythra, merging both of their personalities into one. As the embodiment of the true power of the Aegis, Pneuma is capable of rewriting the physical rules of her surroundings, resulting in all type of feats, from light-speed movement to slowing down time itself. Pneuma is calm and resolute, having lost her insecurities as Pyra and hostility as Mythra upon combining them. She does not appear to view herself as a separate entity to Pyra and Mythra (unlike Pyra and Mythra themselves, who treat each other distinctly), prefers to be called "Pyra" or "Mythra" instead of taking a unique name for herself, and does not remain present for longer than is necessary, favouring being Mythra or Pyra. Pneuma was originally one of three units of the Trinity Processor, alongside the other cores Logos and Ontos. After Klaus activated the Conduit, Pneuma, along with Logos, was modified by the Architect to process data received from the Blade system. Amalthus, with a strong hatred for the world, one day climbed the World Tree in hopes of meeting the Architect and seeking answers. When he arrived at Elysium, he found it empty. As proof of his deed, he took the cores of Pneuma and Logos back to Alrest. Upon arriving in Indol, he awoke Logos, who became known as Malos. Tainted by Amalthus's hatred of the world, Malos set out to destroy Alrest.

Mythra is the Aegis, a Legendary Blade who can grant tremendous fire-elemental power to her Driver, Rex. Pyra and Rex embark on a journey to search for Elysium, and Rex is devoted to protecting her. Due to sharing her life force with Rex, Pyra is not able to recover from injuries like other Blades, and is as vulnerable to damage as any other human. If either of the two were to die, the other would follow. Mythra is confident in herself, reckless, and independent. She has a short temper, a rude disposition, and is not afraid to openly express her thoughts. While during the events of Torna ~ The Golden Country, Mythra is shown to have little sympathy for others, in Xenoblade Chronicles 2 she is much more calm and analytical. Due to the destruction she once caused, Mythra considers herself to be a danger to others, and wants to reach Elysium alongside Pyra to beg the Architect for their death. Unlike Pyra, Mythra is not good at cooking, despite enjoying doing so. It angers her when people dislike the food she prepares. She is also a terrible sleeper, often sleepwalking and snoring among other things.

Pyra is the Aegis, a Legendary Blade who can grant tremendous fire-elemental power to her Driver, Rex. Pyra and Rex embark on a journey to search for Elysium, and Rex is devoted to protecting her. Due to sharing her life force with Rex, Pyra is not able to recover from injuries like other Blades, and is as vulnerable to damage as any other human. If either of the two were to die, the other would follow. Pyra is usually seen to be very doubtful of her worth and considers herself to be a burden and a danger to others. Due to this, she originally wants to go to Elysium alongside Mythra to ask the Architect for their death, which they could normally not obtain due to their condition as Blades. Pyra is a very kind-hearted, mild-mannered, soft spoken young woman who desires peace among both Blades and Drivers. Despite being gentle around people, she is not afraid to fight to protect those she cares about. Pyra is also a very talented cook, and can easily produce delicious food, while Mythra is not good at cooking, despite enjoying doing so, people generally dislike the food she prepares and it angers her. She is also sensitive, as she becomes insulted when Rex calls her "heavy". Pyra was created in the immediate aftermath of the Aegis War, when Mythra became overcome by grief due to her part in the destruction of Auresco; she transformed into Pyra, sealing her Aegis power beneath the second personality. Pyra's driver, Addam, placed Pyra in stasis under the Cloud Sea in order to prevent her from being reawakened and losing control as Mythra did. Addam hoped that when humanity was deemed worthy to wield her power, the Aegis would return and bring them salvation.